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Study Identifies Resveratrol's Ability to Inhibit Cancer

A chemical found in the skin of red grapes and in red wine, is considered to be extremely effective in fighting cancer, even after the metabolism present in the human body converts this chemical into other compounds. Vine Vera reviews a study that was published in the Science Translational Medicine Journal confirms.

This study was conducted by a group of researchers working for the Department of Cancer Studies and Molecular Medicine at the University of Leicester. This study reveals that Resveratrol, a popular antioxidant found in red wine, doesn’t become ineffective after it has been metabolized by the body.

This proves to be an extremely important finding that shows the effectiveness of Resveratrol in the human body, because recent studies had shown that Resveratrol gets metabolized very quickly, thereby raising questions on its effectiveness. This new research also shows that Resveratrol can still be taken in by the cells, even after it has been transformed into Resveratrol sulfates by the body’s metabolism.

The study also shows that enzymes present within the cells manage to break down the Resveratrol sulfates back into Resveratrol. In fact, this study actually shows that Resveratrol might be even more effective once it is transformed from Resveratrol sulfates, because of the higher concentrations.

The team had administered Resveratrol sulfates into mice to further their research. They subsequently managed to detect the presence of free Resveratrol in a variety of tissues and the plasma of mice. This is the first direct sign of the fact that Resveratrol sulfates can be transformed back into Resveratrol by the body, thereby leading researchers to believe that the compound might be even more beneficial than initially thought.

The study also confirmed that the Resveratrol generated from the Resveratrol sulfates can actually slow down the growth of cancer cells by forcing them to digest their own constituents and preventing them from dividing further.

According to Professor Karen Brown, there is some serious evidence from the lab testings that Resveratrol can not just prevent a variety of cancers, but can also protect the body from heart diseases in order to extend the lifespan of the body. It is common knowledge that Resveratrol rapidly converts into sulfates in animals.

This means that the plasma concentrations of Resveratrol become low after administration. Professor Brown states that it was always difficult for experts to understand how Resveratrol managed to offer its benefits when the concentrations were so low. She also mentions that this was one of the main reasons why many experts were doubtful if Resveratrol had any effects whatsoever on humans.

However, the latest study has actually shown that the compound can be regenerated into a more potent form and that this compound can then offer biological activity to the body in order to make itself useful in treating all sorts of diseases. However, most of these discoveries have been made in laboratory settings. Whether or not the compound actually manages to offer such benefits to humans remains to be seen.

Dr. Sarah Williams, the health information officer of Cancer Research UK, mentioned that this study supports the continued research into Resveratrol. She also mentioned that it was important to note that none of the effects were because of drinking red wine and that consuming any sort of alcohol, red wine included, increases the chances of developing cancer.

Resveralife Examines the Connection Between Red Wine and Your Vision

It is a common fact that drinking way too much of alcohol can end up damaging your vision. However, studies have also managed to prove that drinking red wine can actually have a positive effect on your vision as it prevents your eyesight from deteriorating. But, before you open another bottle of red wine to celebrate, let’s read on a bit.

According to a group of researchers affiliated with the Washington University School of Medicine, St. Louis; Resveratrol, a substance that is found in extremely high levels in the skin of red grapes, can prevent the growth of harmful blood vessels. This helps the compound to protect the vessels in your eyes from aging damage. Apart from anti-aging, Resveratrol has been commonly linked to the deterrence of an eye condition known as AMD (Age-related Macular Degeneration) and the prevention of cancer.

Vine Vera reviews reports released by the CDC (Center for Disease Control and Prevention) which state that almost 11 million people suffer from AMD in the US. These reports also suggest that the number of people suffering from AMD should increase to almost 18 million in the year 2050. This disease is basically a condition where a part of the retina (towards the center) as well as the part of the eye which is necessary for sharp vision gets damaged. AMD is also known to be the main cause of vision loss among adults over the age of 50.

According to Sandy T. Feldman, a popular ophthalmologist in San Diego, people have begun to look for ways to prevent and treat common eye disorders including AMD. This new study might come across as a pleasant surprise for all such people because red wine is a favorite for countless people across the globe. To understand that it might have certain health benefits, is certainly pleasing.

Resveratrol is commonly found in the skin of red grapes, but its benefits can also be found in raspberries, cranberries, blueberries and peanuts. Of course, moderation is the key when it comes to any form of alcohol, but it can definitely benefit a person’s vision.

Those of you who are unaware of AMD, here are some of the main symptoms of the disease:

  • Blurry Vision – Blurry vision, dark spots or white spots might occur in your central vision if you’re suffering from AMD.
  • Color Changes – A changed or diminished perception of color is yet another symptom of AMD.
  • Distorted Vision – People suffering from AMD might also begin to suffer from distorted vision as the straight lines may begin to appear distorted.

Ultimately, the best way of ensuring that you protect yourself from eye diseases is to maintain a healthy lifestyle, regulate your diets, add food items that are beneficial for the eyes and perform regular eye exercises. The red wine study certainly comes as an added incentive of taking care for one’s eyes.

Resveratrol's Ability to Treat ANCL

Human prion protein (hPrP), chemical structure. Associated with neurodegenerative diseases, including kuru, BSE and Creutzfeldt-Jakob. Cartoon + wireframe. N- (yellow) to C-term (red) gradient color.Resveratrol, a powerful antioxidant that is found in the skin of red grapes, is extremely famous in the world of skin care because of its unique anti-aging benefits. Recent research now shows that Resveratrol might also be very effective in offering the first cure for a neurodegenerative disease known as ANCL (Adult Onset Neuronal Ceroid Lipofuscinosis).

According to a study that was funded by the BBSRC and AGE UK and was published in the Human Molecular Genetics Journal, a group of University of Liverpool researchers have finally been successful in finding a potential cure for ANCL. Alan Morgan, the lead researcher of this project, states that even though ANCL currently remains to be untreatable, their research allows them to test for compounds that could offer effective treatments. He further states that among all the compounds tested in the first batch, one (Resveratrol) has shown highly encouraging effects.

ANCL is a disease that is known to affect almost 1 out of every 100,000 people in North America and Europe. It mostly affects adults in their mid-thirties and death comes as early as the mid forties. Despite constant research, no cure was found for the disease until now. However, even though previous studies were unsuccessful in finding a cure, they had managed to connect the disease to the DNAJC5 gene.

The latest study used nematode worms to search for cures for the ANCL disease. The disease was introduced into their bodies my mutating the dnj-14 gene, a gene which is quite similar to the DNAJC5 gene in humans. Since these worms have a lifespan of a couple of weeks only, symptoms of the disease were developed within days. This helped in reducing the time frame that was needed to design and study ANCL treatments.

Researchers used this model to test for a number of chemicals. One of the chemicals that was tested on these worms was Resveratrol, and surprisingly, Resveratrol actually managed to cure the disease without even having to act through the SIR-2.1 enzyme. Almost all other potential treatments were forced to act through this enzyme.

These results have encouraged researchers to test for more chemicals and decide whether nematodes can also be used to study for potential treatments against other neurodegenerative diseases that mankind suffers from. These findings go on to suggest that Resveratrol can play a major role in helping humans to prevent diseases and repair the damage caused by diseases. Although scientists have already been studying Resveratrol for many decades, this compound never ceases to amaze.

In fact, in a study conducted in the year 2003, researchers have also managed to prove that using Resveratrol can help in increasing the life span. This was done using short-lived fish as test subjects. Resveratrol helped in increasing their lifespan by as much as 50%. Moreover, the fish that were offered Resveratrol were able to swim and learn new things in their old age better than fish that were not offered Resveratrol.

This leads to the argument that there is still so much more that the world needs to know about Resveratrol. It wouldn’t come as a surprise if we found Resveratrol to become the most important compound known to man in the near future.


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